Vacuum freeze‐drying fa sublimation drying wɔ ɔhyew a ɛba fam ne vacuum kɛse tebea ase. Sɛ wɔde toto atetesɛm mu mframa a ɛyɛ hyew a wɔde dry, spray drying ne mfiridwuma afoforo a wɔde yɛ ɔhyew a wɔde yɛ adwuma ho a, ahoɔden a ɛde di dwuma no dɔɔso koraa. Adwumayɛbea adwumayɛfo pii nya adwene a ɛyɛ pintinn sɛ ahoɔden a wɔde di dwuma no gyina mfiri no din ne ne su so koraa, na baabiara nni hɔ a wobetumi ayɛ no yiye wɔ akyiri yi nneɛma a wɔyɛ mu. Wɔ adeyɛ a wɔyɛ no kɛse ankasa mu no, adwumayɛfo a wɔyɛ adwuma wɔ beae hɔ no adwumayɛ su, tebea a wɔde di kan yɛ nneɛma ho adwuma, ɔkwan a wɔfa so de nneɛma gu mu, freeze‐drying curve nhyehyɛe ne da biara da nsiesie tebea no bɛma wɔanya nkɛntɛnso a ɛda adi pefee wɔ tumi a wɔde di dwuma wɔ nneɛma a wɔawie kilogram biara mu.
Nneɛma a wɔde gu mu density ne laying mode ne nneɛma a ɛwɔ nkɛntɛnso tẽẽ sen biara. Adesoa a ɛboro so anaasɛ nea wɔde gu mu boro so no besiw nsu a ɛyɛ hyew no guankɔbea kwan, ama sublimation drying cycle no akyɛ kɛse, na akɔ so ama frigye nhyehyɛe ne vacuum pɔmpɛ no adwumayɛ bere akɔ soro, na ɛde ahoɔden a wɔde di dwuma no akɔ soro kɛse. Nea ɛne eyi bɔ abira no, sɛ wɔhyɛ nneɛma tray no fã bi pɛ ma a, freeze‐dryer cavity no a wɔde di dwuma no so tew kɛse. Ɛwom sɛ wɔtew bere a wɔde bɛyow wɔ batch biako mu no so de, nanso bere a wɔde yɛ ade biako biara no sua, na ɛno nso piapia ahoɔden a wɔde di dwuma nyinaa wɔ nneɛma kilogram biara mu. Ɛsɛ sɛ wɔn a wɔyɛ adwuma no hwɛ nneɛma no mu duru a ɛyɛ pɛ so, wɔma nsonsonoe a ɛfata si nneɛma no ntam, hwɛ hu sɛ ɔhyew a ɛkɔ baabiara ne nsu a ɛyɛ hyew no trɛw yiye, na wɔma mfiri no tumi de nneɛma a etu mpɔn no yɛ kɛse wɔ adwene a ɛne sɛ wɔbɛma nneɛma a ɛyow no ayɛ papa no ase.
Pre‐freezing procedure yɛ freeze‐drying craft mũ no nyinaa fapem, a ɛwɔ nkɛntɛnso a wontumi mmu ani ngu so wɔ ahoɔden a wɔde di dwuma nyinaa so. Sɛ ɔhyew a ɛwɔ hɔ ansa na awɔw ahyɛ mu no nyɛ nea ɛba fam sɛnea ɛsɛ anaasɛ bere a wɔde kura mu no nnɔɔso a, wontumi nsakra nneɛma no mu nsu koraa nkɔ nsukyenee a ɛyɛ den mu. Ɔfã bi a ɛyɛ nwene adeyɛ bɛba wɔ sublimation fã no mu. Nsu a ayɛ nwini bɛsɛe mfitiase ntini a ɛwɔ abon mu a ɛwɔ nneɛma a wɔde ahyɛ nwini mu no, na nsu a ɛyɛ nsu a wɔsan de yɛ nwini no bɛma ahoɔden foforo a wɔhwere bɛba. Nanso, anifuraefo a wobedi ɔhyew a ɛba fam koraa ansa na awɔw wom akyi nso nyɛ nea wɔpɛ. Ɔhyew a ɛba fam dodo bɛma wɔagye ahoɔden a wɔde yɛ frigye pii a ɛremma mfaso foforo mma nneɛma a wɔyɛ no yiyedi so. Nneɛma ahorow a wɔde yɛ nneɛma a nnuaba, nhabannuru, nam ne nufusu a wɔde yɛ nneɛma ka ho no wɔ eutectic nsɛntitiriw ahorow. Ɛsɛ sɛ adwumayɛfoɔ de targeted pre‐freezing temperature ne holding time sɛdeɛ material eutectic point su teɛ, na ama wɔanya freezing effect a edi mũ a ahoɔden a ɛba fam koraa.
Sɛ nneɛma a wɔde gu mu ne pre‐freezing da nkyɛn a, wontumi mmu ani ngu da biara da nsiesie a wɔyɛ wɔ nneɛma atitiriw no so. Condenser na ɛkyere nsuo a ɛyɛ hyew a ɛfiri nneɛma mu ba no. Sɛ asase ani boaboa awɔw a ɛyɛ den ano a, ɛda adi sɛ ɔhyew a wɔde sesa no yiye no bɛkɔ fam. Vacuum pump, sealing rings ne ɔpon gasket tẽẽ si gyinae vacuum℃mu dan. Mpanyinyɛ, ɔsɛe ne efĩ a ɛboaboa ano wɔ nneɛma a wɔde hyɛ mu no bɛma vacuum a ɛretu. Sɛnea ɛbɛyɛ a wobetumi akura vacuum level a wɔahyɛ no mu no, ɛsɛ sɛ vacuum pump no de adesoa a ɛkorɔn tu mmirika, na ɛde ahoɔden a wɔsɛe no foforo a ɛkɔ so ba. Daa defrosting, condenser ahotew, nhwehwɛmu ne sesa dedaw sealing accessories betumi ama nnwinnade ayɛ adwuma wɔ high‐efficiency tebea.
Wɔhyɛ nyansa sɛ nnwumakuw mfa nneɛma a wɔyɛ ho nsɛm a wɔakora so a edi mũ nsi hɔ. Kyerɛw pre‐freezing parameters, sublimation temperature, processing bere tenten, ankasa tumi a wɔde di dwuma ne finished product quality index ma batch biara a ɛsono raw materials. Nkakrankakra bɔ nhyehyɛe a ɛho akokwaw na ɛyɛ pintinn a ɛfa nneɛma biara ho no mua. Kwati sɛ wobɛsan ayɛ nhwehwɛmu debugging wɔ production batch biara mu. Standardized ne solidified adwumayɛ akwan betumi atew unit ahoɔden a wɔde di dwuma wɔ freeze‐dried nneɛma so nkakrankakra. Wɔ adwumayɛbea dwumadie a ɛkyɛ mu no, ahoɔden a wɔde di dwuma a ɛyɛ fɛ a wɔde di dwuma no de mfasoɔ a ɛbɛkɔ so atew ɛka so bɛba na ahyɛ gua so akansi a ɛwɔ nnuan a wɔayam no nwini a ɛtwa toɔ mu no mu den.
