Vacuum freeze-drying de ne ho to vacuum tebea a ɛkorɔn so na ama wɔahu sɛ nsukyenee ahwehwɛ a ɛwɔ nneɛma mu no sublimation tẽẽ. Sɛ mfiri no nya mmeae a mframa fa mu wie a, abɔnten mframa kɔ so hyɛn dan a wɔde dry no mu. Ɛsɛ sɛ vacuum nhyehyɛe no kɔ so tu mmirika wɔ adesoa kɛse mu na ama wɔakura vacuum bo a wɔde asi wɔn ani so no mu. Ɛda adi sɛ vacuum a ɛnnɔɔso bɛma sublimation rate no ayɛ brɛoo. Nneɛma taa yɛ mpɔtam hɔ nwene, twetwe na ɛhwe ase, na ɛde nneɛma a wɔawie a ɛnyɛ nea ɛfata ba na ɛma pow dodow kɔ soro kɛse. Wɔ nsɛm a emu yɛ den mu no, wɔbɛsɛe nneɛma a wɔde yɛ adwuma no nyinaa.
Vacuum leakage huammɔdi dodow no ara fi sealing nhyehyɛe no mu. Afã horow titiriw a ɛyɛ mmerɛw no bi ne drying chamber pon silicone sealing strip, pipeline flange sealing gaskets, vacuum valve sealing rings, dynamic shaft seals of turnover mfiri. Saa rɔba polymer afã horow yi yɛ adwuma sesa wɔ ɔhyew a ɛba fam, ɔhyew a ɛfata ne nhyɛso nsakrae tebea ase bere tenten. Wɔ bere tenten-dwumayɛ akyi no, ɔhaw ahorow te sɛ hardening, mpaapaemu, deformation, surface adhesion of material residues bɛda adi nkakrankakra. Ntrɛwmu nketenkete a saa sintɔ ahorow yi de ba no bɛyɛ akwan a mframa fa so kɔ mu.
Ɛsɛ sɛ nnwumakuw hyehyɛ nhwehwɛmu kyinhyia ahorow a wɔyɛ no daa wɔ nneɛma a wɔde hyɛ nneɛma mu no ho. Ansa na wɔbɛyɛ batch biara no, ɛsɛ sɛ adwumayɛfoɔ hwɛ sɛ ɔpon no ano aduru no wɔ tebea pa mu anaa, tew pulp debris, sradeɛ ne nkaeɛ foforɔ a ɛbata soro no ho. Amannɔne nneɛma a ɛbɛbata ade a wɔde hyɛ nsɔano no ne rɔba a wɔde abɔ no ntam no bɛma wɔamia nsɔano no a enni mũ na akɔhyɛ nsɔano no mu daa. Sɛ wohu sɛ ɛyɛ den, mpaapaemu ne elastic a ɛyera a, sesa nneɛma a wɔde boa no wɔ bere ano sen sɛ wobɛkɔ so ayɛ.
Wɔ nnwinnade a ɛda adi sɛ vacuum drop wom ho no, ɛsɛ sɛ wɔyɛ adwuma a wɔahyɛ da ayɛ a wɔde hu nsu a ɛretu. Akwan a wɔtaa fa so hu no bi ne static vacuum holding test, spray leak detector nhwehwɛmu. Sɛ wɔto freeze-drying chamber no mu na wɔde pumped kɔ target vacuum no akyi a, twa vacuum system no na kyerɛw vacuum no ahoɔhare a ɛkɔ soro no. Sɛ nhyɛso a ɛkɔ soro no boro nea wɔahyɛ da ayɛ no so a, ɛkyerɛ sɛ ɛda adi sɛ nsu a ɛretu no wɔ hɔ. Afei fa w’adwene si ɔpon no frame, flange biara nkitahodi, valve afã horow a wobɛhwɛ so. Ɛfata sɛ yɛhyɛ no nsow sɛ ahoɔden a ɛboro so bere a wɔreto ɔpon no mu no bɛma nsɔano no asɛe koraa; ɛsɛ sɛ wɔde tumi a ɛfata a wɔde kyekyere nneɛma sie sɛnea nnwinnade ahwehwɛde te.
Nnwumayɛbea pii sesa nneɛma a wɔde boa no bere a nsu a ɛretu kɛse akyi nkutoo, na ɛde asiane ahorow a ɛba bere ne bere mu sɛ nneɛma a ɛyɛ papa bɛsakra wɔ nneɛma a wɔyɛ no mu ba. Sɛ wosiesie no da biara da a, ebetumi ama nneɛma a wɔde ahyɛ mu no nkwa nna akyɛ. Kwati sɛ wode nneɛma a wɔde tew nneɛma ho a ɛyɛ mmerɛw bedi dwuma de aprapra rɔba nsɔano; siw bere tenten-a ɛne srade ne acidic nneɛma nsu a ɛbɛka tẽẽ no ano. Sɛ wopɛ mfiri a wɔde to mu bere tenten a, ma ɔpon no mmue kakra na woakwati bere tenten-nhyɛso deformation a ɛwɔ sealing strip no mu.
Nsɔano a wɔde di dwuma yiye betumi akura vacuum adwumayɛ a ɛyɛ den a ɛwɔ freeze dryer mu no mu, ama nneɛma a wɔde yɛ adwuma no ayow no akɔ so daa, ahwɛ unit ahoɔden a wɔde di dwuma wɔ dodow a wɔhwɛ kwan no mu, na atew nneɛma a wɔyɛ a ɛho nhia a wɔhwere so ama nnwuma a wɔyɛ nnuan a wɔayam no freeze-dried.
