Vacuum freeze dryers yɛ drying mfiri a ɛyɛ adwuma yie a ɛyi nsuo fi nneɛma mu denam low-temperature sublimation so. Wɔde di dwuma kɛse wɔ nnuan, nnuruyɛ, abɔde a nkwa wom, ne nnuruyɛ mu. Wɔn nnyinasosɛm titiriw ne sɛ wɔbɛma nneɛma no hyew akɔ fam asen nwini wɔ baabi a ɛhɔ yɛ hyew, na ama nsu no akɔ soro tẽẽ afi ade a ɛyɛ den mu akɔ tebea a ɛyɛ mframa mu, na wɔnam saayɛ so akwati nneɛma a ɛyɛ adwuma a ɛwɔ ade no mu a ɔhyew a ɛkɔ soro de ba no sɛe. Nea edidi so yi kyerɛkyerɛ ɔkwan a wɔfa so de di dwuma no mu kɔ akyiri fi afã abiɛsa: ahosiesie a wɔyɛ ansa na wɔreyɛ-oprehyɛn, adwumayɛ ho nhyehyɛe, ne ahwɛyiye.
Pre-oprehyɛn Ahosiesie
Nnwinnade a Wɔhwehwɛ: Si so dua sɛ awɔw afiri, vacuum pɔmpɛ, ɔhyew nhyehyɛe, ne nhyehyɛe a wɔde di dwuma no reyɛ adwuma sɛnea ɛsɛ. Hwɛ sɛ awɔw afiri no hyew adu boɔ a wɔahyɛ ato hɔ (mpɛn pii no ɛhia sɛ wɔdi kan -onwini kɔ fam -40℃), sɛ vacuum pump ngo dodoɔ no wɔ standard range no mu, ne sɛ sealing rings no nni dɛm.
Nneɛma a Wɔde Yɛ Pretreatment: Yɛ pre-freezing treatment sɛnea nneɛma no su te. Sɛ nhwɛso no, ɛsɛ sɛ wɔde nnuan nneɛma gu nwini mu wɔ -30℃kosi -40℃nnɔnhwerew 12-24 na ama wɔahwɛ ahu sɛ ayɛ nwini koraa; nnuru a wɔde yɛ nnuru hwehwɛ sɛ wɔhyɛ nwini a wɔahyɛ so na ama ahwehwɛ no ansɛe. Sɛ wɔanhyɛ nwini ansa na wɔayɛ nwini sɛnea ɛsɛ a, ebetumi ama ahwe ase wɔ sublimation fã no mu, na aka nea wɔawie no su.
Loading ne Layout: Fa nneɛma no petepete nneɛma trays no so pɛpɛɛpɛ, na wɔkamfo kyerɛ sɛ ne kɛse yɛ 5-10mm. Ɛsɛ sɛ nneɛma tray ahorow pii kura ntam kwan (sɛ nhwɛso no, 38mm) na wɔakwati sɛ ebesiw vapor diffusion kwan. Sɛ wopɛ nneɛma a ɛwɔ nneɛma a ɛyɛ hyew a, fa nneɛma a wɔde kyekyere nneɛma a mframa tumi fa mu yiye di dwuma.
Nneɛma a Wɔde Di Dwuma
Pre-freezing Stage: Fa intelligent control panel hyehyɛ pre-freezing temperature (-40℃to -50℃) ne bere (sesa sɛnea nneɛma dodow te, mpɛn pii no nnɔnhwerew 2-4). Wɔ saa bere yi mu no, hwɛ hu sɛ afiri a ɛyɛ nwini no hyew no gyina na ama nsukyenee ahwehwɛ a ɛbɛba dodo esiane ɔhyew a ɛsakra nti.
Vacuuming ne Sublimation Drying: Sɛ wodi kan-freezing wie a, hyɛ vacuum pump no ase na ama nhyehyɛe no nhyɛso so atew akodu 10Pa (a wobɛnya standard vacuum a ɛyɛ 5Pa wɔ no-adesoa ase). Saa bere yi de, nsukyenee a ɛwɔ ade no mu no fi ase yɛ kɛse, na ɛhwehwɛ ahoɔden fi ɔhyew nhyehyɛe a ɛma nsu fa mu (sɛ nhwɛso no, shelf heating). Ɛsɛ sɛ wɔma ɔhyew no hyew kɔ soro nkakrankakra (wɔkamfo kyerɛ sɛ wofi ase fi -20℃, kɔ soro digrii 5-10 wɔ ɔfã biara mu) na wɔakwati ɔhyew a ɛboro so wɔ mpɔtam hɔ.
Desorption Drying Stage: Sɛ nneɛma no hyew bɛn baabi a ɛhɔ yɛ hyew a, desorption drying stage no fi ase. Saa bere yi de, ɛsɛ sɛ wɔtew vacuum dodow no so bio (kɔ fam 2 Pa), na wɔmaa shelf hyew no kɔɔ soro kodu digrii 30-50 na ama wɔayi nsu a wɔakyekyere a aka no afi hɔ. Wɔ saa bere yi mu no, ɛsɛ sɛ wɔhwɛ nhwɛsode no hyew a wɔda no adi no so daa na amma ɔhyew a ɛboro so amma nneɛma no nsɛe.
Shutdown and Sampling: Sɛ woyow wie a, di kan dum ɔhyew nhyehyɛe no, na afei dum vacuum pump no bere a nneɛma no hyew akɔ fam akodu dan mu hyew akyi. Awiei koraa no, fa nitrogen a ɛyow hyɛ mu na ama abubu vacuum no na ayi ade no afi hɔ. Wɔ nneɛma a ɛsom bo kɛse-mu no, wɔkamfo kyerɛ sɛ fa one-button electric defrost adwuma no di dwuma na ama mfiri no asan akɔ ne tebea a ɛfata mu ntɛmntɛm.
