ɛsɛ sɛ wɔyɛ dan no mu ɔfasu, tray ne rack weld ahorow no fɛfɛɛfɛ a nsonsonoe anaa amena biara nni mu na ama nkae ne nneɛma a ɛyɛ hua a ɛyɛ hyew a ɛbata ho no so atew. Ɛsɛ sɛ wotumi yi tray ne rack ahorow no mu ntɛmntɛm na ama wɔahohoro afi dan no akyi yiye. Pipe ne cold‐trap bɛboa flushing ne purging. Nnwumayɛbea pii hohoro tray nkutoo nanso wobu wɔn ani gu condenser ne vacuum pipelines so; volatile compounds adsorbed on cold‐trap bɛkɔ so agyae off‐flavor wɔ mmirikatu a edi hɔ no mu. Ɛsɛ sɛ wotumi yi nsɔano nhama no mu de yi nneɛma a asɛe no fi hɔ.
Nea ɛto so abien no, fa nsakrae‐ahotew SOP a wɔahyɛ da ayɛ no si hɔ. Nneɛma ahorow kura asiane‐gyinabea ahorow. Ɛyɛ ahyɛde sɛ wɔbɛhohoro, wɔpopa na wɔhohoro ho koraa bere a wɔresakra afi nnuaba a huam nyɛ den so akɔ ɛpo mu nnuan a ɛyɛ huam denneennen so no. Ɛho hia sɛ wɔhohoro nneɛma a ɛkorɔn bere a wɔresan afi nneɛma a ɛyɛ huam kɛse so akɔ nnuaba a ɛyɛ dɛ a emu yɛ hare so no. Ebia ɛho behia sɛ wɔyɛ blank test‐run de si hua a aka no so dua ansa na wɔde new‐batch aduan ama. Nsu‐hohoro a ɛnyɛ den no nnɔɔso.
Ɛnyɛ den sɛ wobebu ani agu nhyehyɛe a wɔyɛ wɔ nneɛma a wɔyɛ no nnidiso nnidiso so. Hyehyɛ akuwakuw fi hua a emu nyɛ den so kosi hua a ano yɛ den so. Di kan yɛ nnuaba ne ɛmo a ɛyɛ huam a ɛyɛ brɛoo ho adwuma; afei tu durian ne ɛpo mu nnuan a hua a ano yɛ den wom. Ntoatoaso a wɔdannan no bɛma ahotew adwuma ne asiane ahorow a ɛwɔ cross‐flavor mu no akɔ soro kɛse.
Fa batch‐records hyɛ nneɛma a wɔayɛ ho adwuma ne ahotew kum tebea nsow. Bere a wɔasesa akuw a asiane kɛse wom akyi no, wɔhyɛ nyansa sɛ wɔnyɛ nkate mu nhwehwɛmu a ɛnyɛ den ansa na wɔayɛ nneɛma pii. Sɛ wɔka hardware, SOP a wɔhohoro ne nhyehyɛe bom a, freeze dryer biako betumi ahu multi‐material rotation manufacturing dwoodwoo.
